Perfluoroctaansulfonzuur: verschil tussen versies

PFOS is voor [[zoogdieren]], en dus ook de mens, heel schadelijk.<ref name="OECD02">{{Cite journal|author=OECD|datum=|title=Hazard Assessment of Perfluorooctane Sulfonate (PFOS) and its Salt|journal=ENV/JM/RD(2002)17/FINAL|pagina's=5|year=2002}}</ref> De stof verstoort de werking van het [[Endocrien systeem|endocrien stelsel]],<ref>{{cite journal|date=September 2009|title=Thyroid Function and Plasma Concentrations of Polyhalogenated Compounds in Inuit Adults|journal=Environmental Health Perspectives|volume=117|issue=9|pages=1380–1386|pmid=19750101|pmc=2737013|doi=10.1289/ehp.0900633|last1=Dallaire|first1=Renée|last5=Ayotte|first4=Serge|last4=Dery|first3=Daria|last3=Pereg|first2=Éric|last2=Dewailly|first5=Pierre}}</ref> verhoogt het risico op [[cholesterol]],<ref name="Steenland">{{cite journal|date=21 October 2009|title=Association of Perfluorooctanoic Acid and Perfluorooctane Sulfonate With Serum Lipids Among Adults Living Near a Chemical Plant|journal=American Journal of Epidemiology|volume=170|issue=10|pages=1268–1278|pmid=19846564|doi=10.1093/aje/kwp279|last1=Steenland|first1=K.|last5=Vaccarino|first4=A.|last4=Ducatman|first3=S.|last3=Frisbee|first2=S.|last2=Tinker|first5=V.}}</ref> verhoogt de resistentie tegen [[insuline]],<ref name="Nelson">{{cite journal|date=February 2010|title=Exposure to Polyfluoroalkyl Chemicals and Cholesterol, Body Weight, and Insulin Resistance in the General U.S. Population|journal=Environmental Health Perspectives|volume=118|issue=2|pages=197–202|pmid=20123614|pmc=2831917|doi=10.1289/ehp.0901165|last1=Nelson|first1=Jessica W.|last2=Hatch|first2=Elizabeth E.|last3=Webster|first3=Thomas F.}}</ref> heeft een impact op het [[immuunsysteem]] (verminderde weerstand bij [[griep]] en mogelijk ook bij [[COVID-19]], eventueel met verhoogde [[mortaliteit]]<ref>{{cite journal|date=2009|title=Effect of perfluorooctane sulfonate (PFOS) on influenza A virus-induced mortality in female B6C3F1 mice|journal=The Journal of Toxicological Sciences|volume=34|issue=6|pages=687–691|pmid=19952504|doi=10.2131/jts.34.687|last1=Guruge|first7=Noriko|first8=Nobuyoshi|last8=Yamashita|last7=Yamanaka|first1=Keerthi S.|first6=Leo W.Y.|last6=Yeung|first5=Jun|last5=Hasegawa|first4=Kenji|last4=Murakami|first3=Nobuaki|last3=Shimada|first2=Hirokazu|last2=Hikono|doi-access=free}}</ref>), verhoogt het risico op [[ADHD]],<ref>{{cite journal|date=December 2010|title=Exposure to Polyfluoroalkyl Chemicals and Attention Deficit/Hyperactivity Disorder in U.S. Children 12–15 Years of Age|journal=Environmental Health Perspectives|volume=118|issue=12|pages=1762–1767|pmid=20551004|pmc=3002197|doi=10.1289/ehp.1001898|last1=Hoffman|first1=Kate|last5=Vieira|first4=Janice|last4=Weinberg|first3=Marc G.|last3=Weisskopf|first2=Thomas F.|last2=Webster|first5=Verónica M.}}</ref> veroorzaakt mogelijke [[Voortplantingstoxiciteit|fertiliteitsproblemen bij vrouwen]],<ref>{{cite journal|date=April 2009|title=REPRODUCTIVE TOXICOLOGY: Study Associates PFOS and PFOA with Impaired Fertility|journal=Environmental Health Perspectives|volume=117|issue=4|pages=A148|pmc=2679623|doi=10.1289/ehp.117-a148a|last1=Potera|first1=Carol}}</ref> verhoogt de kans op [[Hypertensie|hoge bloeddruk]] en [[pre-eclampsie]] bij zwangere vrouwen<ref>{{cite journal|date=19 August 2009|title=Serum Levels of Perfluorooctanoic Acid and Perfluorooctane Sulfonate and Pregnancy Outcome|journal=American Journal of Epidemiology|volume=170|issue=7|pages=837–846|pmid=19692329|doi=10.1093/aje/kwp212|last1=Stein|first1=C. R.|last2=Savitz|first2=D. A.|last3=Dougan|first3=M.|doi-access=free}}</ref> en eeneventueel mogelijkseen verminderd [[geboortegewicht]].<ref name="Betts2007b">{{cite journal|date=November 2007|title=PFOS and PFOA in Humans: New Study Links Prenatal Exposure to Lower Birth Weight|journal=Environmental Health Perspectives|volume=115|issue=11|pages=A550|pmid=18007977|pmc=2072861|doi=10.1289/ehp.115-a550a|last1=Betts|first1=Kellyn}}</ref><ref>{{cite journal|date=April 2009|title=Correlations between Prenatal Exposure to Perfluorinated Chemicals and Reduced Fetal Growth|journal=Environmental Health Perspectives|volume=117|issue=4|pages=660–667|pmid=19440508|pmc=2679613|doi=10.1289/ehp.11681|first9=Yusuke|first12=Reiko|last12=Kishi|first11=Hiroyuki|last11=Nakazawa|first10=Koichi|last10=Saito|last1=Washino|first1=Noriaki|first8=Ayako|last8=Nakata|first7=Rie|last7=Ito|first6=Kanae|last6=Konishi|first5=Susumu|last5=Ban|first4=Shizue|last4=Kato|first3=Seiko|last3=Sasaki|first2=Yasuaki|last2=Saijo|last9=Iwasaki}}</ref> Bij dierproeven werd [[kanker]] en een toename van de [[neonatale sterfte]] vastgesteld.<ref name="Betts2007">{{cite journal|date=May 2007|title=Perfluoroalkyl Acids: What Is the Evidence Telling Us?|journal=Environmental Health Perspectives|volume=115|issue=5|pages=A250-6|pmid=17520044|pmc=1867999|doi=10.1289/ehp.115-a250|last1=Betts|first1=Kellyn S.}}</ref>